Download BRS Genetics by Dr. Ronald W. Dudek PhD PDF

By Dr. Ronald W. Dudek PhD

Widely utilized by scientific scholars learning for the USMLE Step 1, the Board evaluation sequence (BRS) presents uncomplicated wisdom because it pertains to scientific events. BRS Genetics addresses a box that's more and more taught in shorter classes. Chapters are written in an overview structure and contain pedagogical positive factors corresponding to bolded key terms, tables, algorithms, and various illustrations, together with a 16-page full-color insert. The booklet comprises approximately three hundred USMLE-style inquiries to support try out scholars' memorization and mastery.

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Classic Rett syndrome (CRS). a. CRS is an X-linked dominant genetic disorder caused by various mutations in the MECP2 gene on chromosome Xq28 for methyl-CpG-binding protein 2 (MECP2) which has a methyl-binding domain (binds to 5-methylcytosine rich DNA) and a transcription repression domain (recruits other proteins that repress transcription). The MECP2 protein mediates transcriptional repression of various genes and epigenetic regulation of methylated DNA by binding to 5-methylcytosine rich DNA.

F. Telomerase is utilized by stems cells and neoplastic cells so that chromosomes remain perpetually long. Telomerase may play a clinical role in aging and cancer. IV. TYPES OF DNA DAMAGE AND DNA REPAIR A. Chromosomal breakage refers to breaks in chromosomes due to sunlight (or ultraviolet) irradiation, ionizing irradiation, DNA cross-linking agents, or DNA damaging agents. These insults may cause depurination of DNA, deamination of cytosine to uracil, or pyrimidine dimerization, which must be repaired by DNA repair enzymes.

A) (B) (C) (D) (E) 0% 25% 50% 75% 100% 17. What is Cassie and Blain’s son’s (the fraternal twin) risk to have hemophilia A? (A) 0% (B) 25% (C) 50% (D) 75% (E) 100% 18. How are Barbara and Blaine related? (A) (B) (C) (D) first cousins first cousins once removed second cousins second cousins once removed 19. Fragile X syndrome is one of the most common causes of mental retardation in humans. It generally acts like an X-linked recessive disease, but some males do not have the disease yet they can pass it on, and some females are affected.

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